SK Renewal 40 — Advanced Keratolytic Cream For Rough, Raised Seborrheic Keratoses
SK Renewal 40 — Advanced Keratolytic Cream For Rough, Raised Seborrheic Keratoses
40% urea is the #1 dermatologist-recommended keratolytic concentration for stubborn skin growths.
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Why Freezing, Scraping & Home Remedies Don't Work
Why Freezing, Scraping & Home Remedies Don't Work
Cryotherapy, curettage, and Eskata all target the surface — the growth you can see. But seborrheic keratoses are built from compacted keratin that starts deep in the skin. Removing the top layer doesn't stop new keratin from piling up underneath.
Home remedies like ACV, Compound W, and hydrogen peroxide can burn surrounding skin and still leave the structure intact. That's why growths keep coming back — or leave white spots and scars behind.
How 40% Urea Actually Works
How 40% Urea Actually Works
Urea is a keratolytic — it dissolves the bonds holding compacted keratin together. At 40%, it reaches the concentration dermatologists recommend for stubborn, built-up growths.
Combined with 2% salicylic acid, it softens and loosens the hardened layers so your skin can shed them naturally. No freezing, no scarring, no one-spot-at-a-time treatments.
How Long Will It Take To See Results?
How Long Will It Take To See Results?
Most women notice the rough, raised texture starting to soften within the first 2–3 weeks. Thinner growths may flatten noticeably by week 4–6.
Thicker, more stubborn keratoses — especially on the back and torso — typically take 6–10 weeks of consistent nightly use. Give it a full 90 days for the best picture of what it can do.
Can I Use It On Large Areas Of My Body?
Can I Use It On Large Areas Of My Body?
Yes — that's exactly what it's designed for. Unlike cryo or curettage that treat one spot at a time, this cream spreads across your entire back, chest, arms, or legs in minutes.
If you have dozens or hundreds of growths, you don't need to choose which ones to treat first. Apply it everywhere you need it, every night.
Is It Safe For Sensitive Skin?
Is It Safe For Sensitive Skin?
40% urea is strong enough to dissolve compacted keratin but gentle on healthy surrounding skin. It's non-irritating, fragrance-free, and won't cause the burns or white spots that come with freezing or chemical peels.
If you have very sensitive skin, start every other night for the first week and build to nightly use.
Ingredients
Ingredients
Two active ingredients. Clinical-strength, nothing hidden.
Primary Active: 40% Urea (keratolytic)
Secondary Active: 2% Salicylic Acid (exfoliant)
Size: 4 oz / 113 g
Made In USA · FDA Registered Facility
40% urea is the #1 dermatologist-recommended keratolytic concentration for stubborn skin growths. Paired with 2% salicylic acid to accelerate natural shedding. No fragrance, no fillers, no irritants.
SK Renewal 40 — Advanced Keratolytic Cream For Rough, Raised Seborrheic Keratoses
Real women, real results
"done paying $500 per area to freeze them off"
Spent thousands at the derm getting them frozen one at a time. They always came back. Six weeks of this on my whole back and chest and the rough patches are flattening on their own. No white spots.
"finally something for all of them at once"
Cryo treats one at a time for $250 a pop. I have them on my arms, back, and legs. This is the first thing I can spread across an entire area instead of playing whack-a-mole at the derm every six months.
"my back is mine again"
I'd stopped wearing anything sleeveless because of these things on my upper arms. Month two and my skin feels smoother than it has in years. My daughter noticed before I did.
Why Freezing & Scraping Don't Work — And What Does
Cryotherapy, curettage, and Eskata all target the surface — the growth you can see. But seborrheic keratoses are built from compacted keratin that starts deep in the skin. Remove the top layer and more keratin just piles up underneath.
40% urea is a keratolytic — it dissolves the bonds holding that compacted keratin together so your skin sheds it naturally. No freezing, no white spots, no one-growth-at-a-time office visits.
Dissolves compacted keratin — not just the surfaceCovers your whole back, chest, or arms in minutesNo scarring, no white spots, no $250-per-spot office bills
40% UREA + 2% SALICYLIC ACID
Break Down Roughness. Bring Back Smoother Skin.
Thick, rough skin can build up when dead skin cells accumulate on the surface. Our formula combines 40% urea to help soften hardened areas with 2% salicylic acid to exfoliate dead skin buildup. Together, they help dry, rough skin feel smoother and more hydrated.
Softens
Rough Skin
Hydrates
Dry Areas
Exfoliates
Buildup
Smoother
Skin Texture
Urea to help soften thick, rough skin
Salicylic acid for exfoliating dead skin buildup
Generous jar for your skincare routine
Exfoliation and intensive hydration
Powerful Formula.
Targeted Body Care.
Smoother-Feeling Skin.
A concentrated blend of 40% urea and 2% salicylic acid helps soften stubborn roughness while exfoliating dead skin buildup. Designed for thick, dry areas like heels, elbows, and knees.
Everything you want to know before trying 40% urea cream for seborrheic keratosis.
Frequently Asked Questions
Can I use this on my face?
Can I use this on my face?
40% urea is formulated for body skin — chest, back, arms, legs, and torso. The skin on your face is thinner and more sensitive. For facial seborrheic keratoses, we recommend consulting your dermatologist. Most customers use this cream on body areas where growths tend to cluster the most.
How long before I see results?
How long before I see results?
Most women notice visible softening and flattening within 2–6 weeks of consistent nightly use. Thinner, newer growths tend to respond first. Thicker, more established growths may take 6–10 weeks. The keratin is dissolving from the top down — you'll feel the texture change before the visual change catches up.
Will this leave white spots or scarring like cryo does?
Will this leave white spots or scarring like cryo does?
No. Cryotherapy freezes the growth and the healthy skin around it, which often causes hypopigmentation — those pale white spots that never tan again. Urea works differently. It's a keratolytic — it dissolves the compacted keratin protein without damaging the living skin underneath. No blistering, no scabbing, no white marks left behind.
I have 30+ growths. Can I treat them all at once?
I have 30+ growths. Can I treat them all at once?
That's exactly what this is designed for. Cryo and Eskata treat one spot at a time — at $250–$500 per spot. This cream covers your entire chest, back, or arms in minutes. Most customers with high-volume growths say this is the first time they've been able to address all of them at once instead of picking and choosing which ones to freeze.
How is this different from the urea creams at CVS or Amazon?
How is this different from the urea creams at CVS or Amazon?
Most drugstore urea creams are 10–20% concentration — good for dry heels, not strong enough for seborrheic keratosis. The clinical threshold for keratolytic action is 40%. Ours hits that concentration and pairs it with 2% salicylic acid to accelerate the exfoliation process. It's the difference between a moisturizer and a treatment.
What is your return policy?
What is your return policy?
90-day money-back guarantee. Thicker growths can take 6–10 weeks to fully respond, so we give you 90 days to see real results. If you're not satisfied, contact us for a full refund. No questions asked.
My dermatologist said these are "just cosmetic." Should I still treat them?
My dermatologist said these are "just cosmetic." Should I still treat them?
We hear this constantly. Seborrheic keratoses are benign — but "cosmetic" doesn't mean they don't affect your life. If you've stopped wearing sleeveless tops, avoid the pool, or dread someone noticing the growths on your back — that's not cosmetic. That's quality of life. You deserve to feel comfortable in your own skin again.
The Science Behind Softer, Smoother Skin — Powered by Proven Ingredients
Urea has been used in dermatology for decades to help manage dry, thickened skin. At higher concentrations, it acts as a keratolytic — helping loosen built-up dead skin cells while attracting moisture to the skin.
At 40%, urea helps soften stubborn, hardened areas. Paired with 2% salicylic acid, which supports exfoliation, the formula targets the rough, flaky buildup that ordinary moisturizers may leave behind.
WHY THIS COMBINATION WORKS
Urea softens and hydrates. Salicylic acid helps loosen dead skin buildup. Together, they provide a dual-action approach to improving the feel and texture of thick, rough skin.
40% UREA + 2% SALICYLIC ACID
Stop Living With Rough Skin. Start Feeling the Difference.
Stubborn rough heels, dry elbows, and thickened skin deserve more than ordinary moisturizer. Experience the power of 40% urea + 2% salicylic acid to help soften, exfoliate, and deeply hydrate rough skin.
They Watched Them Dissolve. You Will Too.
"I can run my hand across my back and feel smooth skin again."
Had about 40 growths across my upper back and shoulders. My husband applied this every night for five weeks. The texture changed first—they went from rough and raised to flat and smooth. Three of the smaller ones are completely gone. First time in years I can run my hand across my back and feel normal skin.
"Saved me thousands compared to cryo."
My derm wanted $300 per spot and I had over 20 on my chest alone. That's $6,000 just for my chest. This cream was under $40 and covered everything. Four weeks in and the smaller ones are already shedding. Can't believe I almost paid for cryo.
"My doctor told me to just live with them. No thanks."
Two dermatologists told me they were cosmetic and insurance wouldn't cover removal. One said to "just live with them." I'm 67 with growths on my neck, chest, and under my bra line. This cream softened the ones under my bra line in three weeks—the ones that caught on my clothes every single day. Not living with them anymore.
"I wore a tank top for the first time in four years."
The growths on my upper arms and shoulders made me self-conscious every summer. After six weeks of this cream, the texture is almost completely flat. I wore a sleeveless top to my granddaughter's birthday party and didn't think about it once. That's the real result.
"Tried ACV, Compound W, and two rounds of cryo. This actually worked."
I tried every home remedy on the internet first. Apple cider vinegar burned my skin. Compound W did nothing. Two rounds of cryo left white spots that look worse than the growths. This cream is the first thing that dissolves them without damaging the skin around them. Wish I'd found it years ago.
"My husband noticed them shrinking before I did."
He's the one who applies it on my back every night. Around week four he said these are definitely getting smaller. I couldn't see them myself but I could feel the difference—less rough, less raised. By week eight the largest one on my shoulder blade was half the size it was.
"I stopped covering up at the pool."
Every summer I'd wear a swim shirt or a cover-up because of the growths on my chest and upper back. After two months of this cream the texture is so much smoother that I actually went to the pool in just a swimsuit last weekend. My sister asked what I'd been using. Already ordered her a jar.
"Better than the $500 Eskata treatment my derm pushed on me."
Paid $500 for Eskata on three spots. It worked on one. The other two came back within six months. This cream treats everything for a fraction of the cost and I can apply it myself at home. Wish someone had told me about urea before I wasted money on in-office procedures.
"It dissolved what cryo couldn't reach."
I had cryo done on the spots on my décolletage but my derm said the ones on my back were too many to treat in one session. So they just left them. This cream covers my entire back in two minutes. After six weeks the growths are noticeably flatter and the skin feels smoother. No white spots, no scarring.
"The 90-day guarantee is why I tried it. The results are why I stayed."
I've wasted money on so many "keratosis removal creams" from Amazon that did nothing. The guarantee gave me confidence to try one more. By week three the smaller growths on my arms were softening. By week eight most were flat. I'm on my third jar and haven't thought about returning it once.
"It works but the thick ones take time."
The smaller, thinner growths softened within three weeks. But the big thick one on my sternum barely budged until week seven. It's working—just slowly on the larger ones. Be prepared to be patient with the stubborn spots.
"Wish the jar was bigger."
The cream works well but the jar is small when you're covering a large area every night. I go through it in about three weeks treating my back and chest. Wish they had a bigger size or a multi-pack option. Still reordering because it's working.
"I almost gave up at week two."
Nothing happened for the first two and a half weeks. I almost threw it out. Then around week three I noticed the edges of the growths on my arms were peeling slightly. By week six most of them are flat. It works but you have to push through the waiting period.
"Softens them but doesn't fully remove the big ones."
It definitely softened and flattened most of my growths. But the two really thick raised ones on my mid-back are still there, just smaller and smoother. For the big ones you might still need cryo. But for the dozens of smaller ones this is honestly a game changer.
"Good product but apply sparingly—a little goes a long way."
I used way too much the first week and the healthy skin around the growths got a little dry and flaky. Cut back to a thin layer just on the growths and it worked perfectly with no irritation. The product works, just don't glob it on like I did.